The Early Origins of Cardiovascular Disease

Danone Institute International

Status: Unknown

Conditions: Cardiovascular Disease

Study type: Observational

Funder types: Other

Identifiers

NCT00923039

NU 304

Details and patient eligibility

About

Small body size at birth, slow weight gain during infancy and increase in body mass index after 2 years are independent risk factors for cardiovascular disease and the metabolic syndrome. There is a large gap in our understanding of how early growth affects the cardiovascular system. Possible mechanisms include alterations in body composition, in cardiac structure, in vascular function, in renal function and epigenetic processes.

The Objective is to determine how size at birth and growth during infancy and childhood affect: body composition, cardiac structure and function, vascular and endothelial function, renal function, metabolic status and transcriptional and epigenetic characteristics.

Enrollment: 200 estimated patients

Sex: All

Ages: 18 to 25 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Male and female volunteers students aged between 18-25 years old
• Having growth records

Exclusion criteria

• If young women subject without contraception,or pregnant

Trial design

200 participants in 1 patient group

Exposed/ Not exposed