The EBC Recovery Study

University of Miami

Status: Enrolling

Conditions: Intracerebral Haemorrhage; Subarachnoid Haemorrhagic Stroke; Traumatic Brain Injury

Treatments: Diagnostic Test: Auditory stimuli

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT04712591

20191143

Details and patient eligibility

About

The purpose of this research study to find out if clinically unconscious acute brain injury patients that show brain activation to music and language on electroencephalogram (EEG) (bedside test) have better outcomes and wake up in the future.

Enrollment: 300 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

For ABI Participants

• ABI adult (18 years and older) patients who are admitted to the intensive care unit
• Unconscious with Glasgow Coma Scale (GCS) <8 on presentation and unable to follow bedside commands.
• A negative COVID-19 test on arrival

For Healthy Volunteers:

• 18 years and older

Exclusion criteria

For All Participants:

• <18 years of age
• Pregnant woman
• Patients with cardiac arrest on presentation

Trial design

300 participants in 2 patient groups

Acute Brain Injury Patients

Description:

Acute brain injury (ABI) patients will be recruited and studied using electroencephalogram (EEG) to monitor their brain response to auditory and visual stimuli.

Treatment:

Diagnostic Test: Auditory stimuli

Healthy Volunteers

Description:

Healthy volunteers will serve as the control group and will undergo electroencephalogram (EEG) to monitor their brain response to auditory and visual stimuli.

Treatment:

Diagnostic Test: Auditory stimuli