The ECOVITA Study - Validation of LUS Score in SARS-CoV-2 Disease, i.e COVID-19

University of Campania "Luigi Vanvitelli"

Status: Unknown

Conditions: Respiratory Distress Syndrome

Treatments: Diagnostic Test: lung ultrasound

Study type: Observational

Funder types: Other

Identifiers

NCT04871685

Vanvitelli

Details and patient eligibility

About

Lung Ultrasound (LUS) has been revealing an extremely useful tool to identify and monitor complications from Sars-COV-2 disease. Recently, a research group has proposed a score, named LUS Score, able to optimize the use of this diagnostic technique. LUS Score is computed analyzing chest posterior and lateral spaces, considering the number of artefacts generated by the inflammed interstitium (B lines), the characteristics of the pleural line and the presence or not of consolidation areas.

The comparison between LUS and chest tomography (CT), the current gold standard for the diagnosis of interstitial pneumonia by COVID-19, has confirmed from the preliminary data, the reliability of such technique. Hence, the validation on a really large sample size of the ultrasound tool performed by dedicated personnel with high expertise, may allow the validation both in the clinical practice and in emergency and ordinary wards.

Enrollment: 950 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• men and women;
• confirmed COVID19 diagnosis after nasal-oropharyngeal swab;
• any symptom at hospitalization
• any therapy
• any pre-existing comorbidity

Exclusion criteria

• pregnant women
• healthy subjects with other respiratory diseases different from COVID-19

Trial design

950 participants in 9 patient groups

Covid Center UOC Vanvitelli, Naples

Description:

Patients hospitalized due to Sars-Cov-2 disease either in emergency or ordinary medicine/intensive care units

Treatment:

Diagnostic Test: lung ultrasound

Covid Center Cotugno Hospital, Naples

Description:

Patients hospitalized due to Sars-Cov-2 disease either in emergency or ordinary medicine/intensive care units

Treatment:

Diagnostic Test: lung ultrasound

Covid Center "Del Mare Hospital", Naples

Description:

Patients hospitalized due to Sars-Cov-2 disease either in emergency or ordinary medicine/intensive care units

Treatment:

Diagnostic Test: lung ultrasound

Covid Center Santa Maria delle Grazie Hospital, Pozzuoli

Description:

Patients hospitalized due to Sars-Cov-2 disease either in emergency or ordinary medicine/intensive care units

Treatment:

Diagnostic Test: lung ultrasound

Covid Center Monaldi Hospital, Naples

Description:

Patients hospitalized due to Sars-Cov-2 disease either in emergency or ordinary medicine/intensive care units

Treatment:

Diagnostic Test: lung ultrasound

Covid Center Vannini Hospital, Rome

Description:

Patients hospitalized due to Sars-Cov-2 disease either in emergency or ordinary medicine/intensive care units

Treatment:

Diagnostic Test: lung ultrasound

Covid Center Bassini Hospital, ASST Milano Nord

Description:

Patients hospitalized due to Sars-Cov-2 disease either in emergency or ordinary medicine/intensive care units

Treatment:

Diagnostic Test: lung ultrasound

Covid Center Melfi Hospital

Description:

Patients hospitalized due to Sars-Cov-2 disease either in emergency or ordinary medicine/intensive care units

Treatment:

Diagnostic Test: lung ultrasound

Covid Center Messina University Hospital

Description:

Patients hospitalized due to Sars-Cov-2 disease either in emergency or ordinary medicine/intensive care units

Treatment:

Diagnostic Test: lung ultrasound