The Effect and Prognosis of Different Operations on Varicocele - a Single-center Clinical Study

Sun Yat-sen University

Status: Unknown

Conditions: Varicocele; Male Infertile;Varicocelectomy

Treatments: Procedure: open operation; Procedure: microsurgery

Study type: Interventional

Funder types: Other

Identifiers

NCT01757548

S2011010005282

Details and patient eligibility

About

The purpose of this study is to determine whether high ligation of spermatic vein by open operation and microsurgery for patients with are effective in the treatment of varicocele and to determine which surgical option is better.

Enrollment: 1,000 estimated patients

Sex: Male

Ages: 10 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 1.infertile patient suffering from varicocele 2.severe varicocele patient with obvious symptoms 3.adolescents suffering from severe varicocele with or without orchiatrophy

Exclusion criteria

• 1.varicocele patient with abdominal infection 2.varicocele patient who has massive adhesion of pelvic tissue due to pelvic surgery history 3.mild varicocele 4.varicocele patient has no obvious symptoms if has have born children, suffer from idiopathic azoospermia，or their partner can't bear children

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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1,000 participants in 2 patient groups

open operation

Experimental group

Description:

high ligation of spermatic vein by open operation

Treatment:

Procedure: open operation

microsurgery

Experimental group

Description:

high ligation of spermatic vein by microsurgery

Treatment:

Procedure: microsurgery