The Effect of 40 Hz Transcranial Stimulation on the Incidence of Delirium After Total Hip Replacement or Total Knee Replacement Arthroplasty in Elderly Patients.

Zhengzhou University

Status

Enrolling

Conditions

Elderly

Postoperative Delirium

Anesthesia

Treatments

Device: 40Hz stimulation

Study type

Interventional

Funder types

Other

Identifiers

NCT06522087

Henan BJ

Details and patient eligibility

About

Delirium is an acute confusional state, it is a sign of acute encephalopathy, also known as acute brain failure, acute brain dysfunction or mental state changes.Postoperative delirium can cause post-traumatic stress disorder, affects patients' quality of life, extend the length of hospital stay, increased hospitalization cost, and is closely relative to short-term and long-term mortality after surgery. Exogenous 40 Hz stimulation can improve cognitive functioning. Therefore, the aim of this study was to investigate the effect of exogenous 40Hz stimulation on the incidence of postoperative delirium in elderly patients undergoing hip and knee replacement.

Enrollment

110 estimated patients

Sex

All

Ages

65 to 85 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

1.65-85 years old, gender not limited 2.General anesthesia unilateral total hip replacement surgery or unilateral total knee replacement 3.ASA classification I-III 4.No drugs for mental and central nervous system diseases were used before surgery 5.Preoperative MMSE score illiterate > 17 points, primary > 20 points, junior high school and above > 24 points 6.Obtaining informed consent

Exclusion criteria

Severe liver and kidney dysfunction
here were mental and nervous system diseases before operation
Have a history of alcoholism, long-term use of sedative or analgesic
A history of a delirium and other reasons are reluctant to cooperate
Massive blood loss and blood transfusion during operation, prolonged operation time