The Effect of 5-FU and LMW Heparin on the Rate of Retinal Redetachment After Silicone Oil Removal in Cases of PVR

Shahid Beheshti University of Medical Sciences

Status and phase: Unknown; Phase 3

Conditions: Proliferative Vitreoretinopathy

Treatments: Drug: low molecular weight heparin, 5-FU

Study type: Interventional

Funder types: Other

Identifiers

NCT00371020

8373

Details and patient eligibility

About

To evaluate the effect of combined 5-FU and low molecular weight heparin in infusion on the rate of retinal redetachment after silicone oil removal in cases of proliferative vitreoretinopathy (PVR).

Sex: Male

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Cases with history of vitrectomy and silicone oil injection for management of PVR who undergo silicone oil removal

Exclusion criteria

• any sign of retinal redetachment before silicone oil removal
• any sign of diabetic retinopathy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind