The Effect of a Natural Polyphenolic Extract From Pomegrnate (POMX) on the Development of Atherosclerosis in Diabetic Patients

HaEmek Medical Center, Israel

Status and phase: Unknown; Phase 4

Conditions: Atherosclerosis

Treatments: Drug: POMx

Study type: Interventional

Funder types: Other

Identifiers

NCT00470808

0051-07-EMC

Details and patient eligibility

About

Diabetes is a highly atherogenic disease. Pomegranate juice has impressive antioxidant properties. It has been proven to decrease oxidant stress and to cause the regression of atherosclerotic plaques in hypercholestrolemic and diabetic patients.Furthermore it has been proven to potentiate the biologic activity of the enzyme paraoxonase 1 which is very important in preventing atherosclerosis. The study will try to prove that a polyphenolic extract from pomegranate (POMx) has the same desired effects.

Sex: Male

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Males
• HBA1C>7%
• Drug therapy given for DM

Exclusion criteria

• Age<18
• Inclusion in another study

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)