The Effect of a Phospholipid Drink on Cognitive Performance Under Acute Stress

University of Leeds

Status: Completed

Conditions: Cognitive Performance (Focus)

Treatments: Dietary Supplement: Phospholipid drink; Dietary Supplement: Placebo milk drink

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT01879813

Stress and cognition study

Details and patient eligibility

About

The study will explore the effects of a 6-week phospholipid drink intervention on the cognitive performance and physiological and subjective stress parameters of males following a repeated psychosocial/physical stressor.

Full description

The study conforms to a randomised, double-blind, placebo controlled, parallel groups design examining cognitive performance and physiological/subjective stress responses after a psychosocial/physical stressor before and after a six week daily intake of an phospholipid containing drink vs. placebo.

The study will examine:

Cognitive performance following acute stress prior to, and following 6-weeks intake of a phospholipid containing drink or a placebo analogue.

Physiological and subjective stress responses following acute stress prior to, and following 6-weeks intake of a phospholipid containing drink or a placebo analogue

Enrollment: 54 patients

Sex: Male

Ages: 18 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Male ≥18 years old
• Healthy (self-report health questionnaire)
• BMI <30 kg/m²
• Free from medication (prescribed and 'over-the-counter')

Exclusion criteria

• Current psychological affective/mood disorders
• Self-reported physical disorder/disease (significant cardiovascular, autoimmune, endocrine, gastrointestinal or neurological conditions, chronic pain, or sleep disorders)
• High chronic stress
• Smokers
• Recreational drug use (within the last month)
• Night shift work
• Hypertension (resting blood pressure exceeding 160/95 mmHg)
• Skin conditions (e.g. eczema) on hands
• Food allergies
• Participation in a clinical study within a month prior to screening or during participation
• Participation in any of our previous stress induction studies

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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54 participants in 2 patient groups, including a placebo group

Phospholipid drink

Active Comparator group

Description:

Participants will consume a phospholipid drink daily for 6 weeks

Treatment:

Dietary Supplement: Phospholipid drink

Placebo milk drink

Placebo Comparator group

Description:

Participants will consume a placebo drink (no added phospholipids) daily for 6 weeks

Treatment:

Dietary Supplement: Placebo milk drink