The Effect of a Predictive Model of Bowel Preparation Based on Procedure-related Factors

Air Force Military Medical University of People's Liberation Army

Status: Completed

Conditions: Predictive Model; Bowel Preparation; Colonoscopy

Treatments: Drug: Polyethylene glycol

Study type: Interventional

Funder types: Other

Identifiers

NCT04434625

KY20200614-3

Details and patient eligibility

About

The rate of adequate bowel preparation is one of important quality indicators of colonoscopy. Inadequate bowel preparation negatively affects the outcomes of colonoscopy. If patients with inadequate bowel preparation were identified before the procedure, enhanced strategy could be offered to achieve better bowel cleaning. Currently, there were three predicting models of inadequate bowel preparation established based on patient-related factors. So far, none of predictive models have been tested in other than their validation cohort populations, and no study has attempted to apply a different regimen to patients presenting with risk factors for inadequate colon cleanliness. In previous studies, we established a prediction model based on procedure-related factors, which has better accuracy and can better predict the quality of bowel preparation.

The aim of this study is to compare the quality of bowel preparation by using a predictive model based on procedure-related factors versus the criterion group in unsedation patients

Enrollment: 900 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age: 18~75 years
• Patients undergoing morning colonoscopy

Exclusion criteria

• colon resection;
• suspected bowel obstruction;
• moderate or severe complications related to drinking the 1st or 2rd dose of PEG
• hemodynamically unstable;
• lactating or pregnant women;
• no need to reach the ileocecal segment
• unwilling to provided informed content.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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900 participants in 2 patient groups

control group

No Intervention group

Description:

Colonoscopy was performed in the control group directly.

model-based interference group

Experimental group

Description:

Patients with score ≥3 were asked to taking another dose of PEG (1.5L) within 1-2 hours. Colonoscopy was performed in afternoon (about 4h after drinking PEG). Patients with score\<3 in IM group colonoscopy directly.

Treatment:

Drug: Polyethylene glycol