The Effect of a Prolonged Peripheral Nerve Block on the Level of Pain After a Knee Replacement

Shamir Medical Center (Assaf-Harofeh)

Status: Not yet enrolling

Conditions: Knee Replacement Surgery

Treatments: Drug: Continues peripheral block

Study type: Interventional

Funder types: Other

Identifiers

NCT06382285

0206-22-ASF

Details and patient eligibility

About

The aim of this study is to examine the effect of a prolonged peripheral nerve block (utilizing continuous adductor canal block) on the level of pain after a knee replacement surgery

Full description

Knee replacement surgery is one of the common orthopedic surgeries for the treatment of chronic knee pain. The period after knee replacement surgery is accompanied by moderate to severe pain that affects the patient's ability to quickly return to function. Peripheral nerve blockers and analgesia of different types, administered as part of the anesthesia process, are optimal in controlling pain after surgery. After the surgery, the patients are admitted in the orthopedic inpatient department for 2-3 days on average after surgery for follow-up and early physical therapy necessary to achieve good results and return the patient to full function as soon as possible. The level of pain greatly affects the success rate of the patient's rehabilitation. Thus, since the duration of peripheral nerve block activity does not exceed 8-16 hours on average, it is suggested to treat the patients with a prolonged peripheral nerve block (utilizing continuous adductor canal block) for 24 hours after surgery.

Enrollment: 50 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Female and male patients between the ages of 18 and 80 who have signed an informed consent form.
• ASA is less than 3
• Spinal anesthesia

Exclusion criteria

• Patients with sensitivity to the anesthetic.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

---

50 participants in 2 patient groups, including a placebo group

Treatment group

Experimental group

Description:

ropivacaine (Naropin) 0.2% according to a protocol 8-10 cc per hour up to 24 hours after the surgery

Treatment:

Drug: Continues peripheral block

Control group

Placebo Comparator group

Description:

Saline according to a protocol 8-10 cc per hour up to 24 hours after the surgery

Treatment:

Drug: Continues peripheral block