The Effect of Active Nutritional Support On Quality Of Life In Patients With Head And Neck Cancer Receiving Radiotherapy

Assiut University

Status: Completed

Conditions: Head and Neck Neoplasms

Treatments: Dietary Supplement: various available nutrition as those contain high protein content as ensure milk

Study type: Interventional

Funder types: Other

Identifiers

NCT06477341

RMAHassan

Details and patient eligibility

About

note effect of appropriate nutrition on head and neck cancer patients receiving radiotherapy

Full description

Head and neck cancer (HNC) is the sixth most common cancer worldwide with more than half a million new cases diagnosed each year . Because of the limitations imposed by the complicated anatomical structure of the head and neck to the operation, radiotherapy (RT) has become the main treatment method for HNC. However, damage to the normal tissue surrounding the tumor is inevitable. The most common manifestations of injury caused by RT are mucositis with the dry mouth, loss of taste, and dysphagia. The severe dysphagia leads to a definitive total impossibility of eating through the mouth in 20-30% of patients. Radiation-induced oral mucositis (RIOM) is a common side effect after radiotherapy (RT) in head and neck cancer (HNC) patients. RIOM patients with severe pain have difficulty in eating, which increases the incidence of malnutrition and affects patients' quality of life and the process of RT.

Enrollment: 47 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• head and neck cancer patients with age >18
• Newly diagnosed head and neck cancer patients
• histological proven HNC cancer
• head and neck cancer patients treated with radiotherapy or chemo radiotherapy

Exclusion criteria

• Advanced and Metastatic head and neck cancer patients
• head and neck cancer patients treated with chemotherapy only

Trial design

Primary purpose: Supportive Care

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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47 participants in 2 patient groups

control group

No Intervention group

Description:

patients of head and neck cancer receiving radiotherapy , who did not receive any nutritional support during radiotherapy

nutritional support grouped

Active Comparator group

Description:

patients of head and neck cancer receiving radiotherapy , who receive any nutritional support during radiotherapy whether oral or intravenous like dipeptivine for mucositis

Treatment:

Dietary Supplement: various available nutrition as those contain high protein content as ensure milk