The Effect of Acupoint Massotherapy on Relieving Chemotherapy-induced Myelosupression

Taipei Medical University

Status: Unknown

Conditions: Hematopoiesis; Cancer, Breast; Acupressure

Treatments: Device: The Electric vibrating massager,SAMPO®

Study type: Interventional

Funder types: Other

Identifiers

NCT02964286

TMU-JIRB: 201501030

Details and patient eligibility

About

In this proposed project, the investigator will estimate the effect of massotherapy of acupoints on alleviating chemotherapy-induced myelosuppression among patients with cancer.

Full description

Chemotherapy is mainly used to treat and control the progression of gynecological cancer, bone marrow suppression the evil side effects after chemotherapy, which may decreasing immune function and further causes serious fatal infections.

Acupuncture is a valid intervention in medical practice and has been used for the improvement of chemotherapy-induced leucopenia. In a systematic meta-analysis study showed that acupoints stimulation has immunomodulatory effect for therapy induced bone marrow suppression in cancer patients. Therefore, in the acupressure group, the technique used is the electric vibrating massager, and patients are taught to apply the strong mode on the 15 specific points,5 min each, 3 times a day during chemotherapy.The intervention follows the points are used to stimulate the hematopoietic function including Hegu (LI4), Quchi (LI11), Xuehai (SP10); Sanyin-jiao (SP6), Taixi (K3), Zusanli(ST36), Taichong (LV3); and Baihui (GV20). The patients of the control group are not admitted any acupoints press-related interventions mentioned above.

The purpose of this study is to evaluate the effectiveness of non-invasive acupressure on the prevention of chemotherapy-induced myelosuppression among patients with cancer.

Enrollment: 200 estimated patients

Sex: Female

Ages: 20 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• newly diagnosed of gynecologic cancer, regardless of stage.
• receiving initial chemotherapy.
• ability to write informed consent.
• between 20 to 70 years old.

Exclusion criteria

• history of severe cardiac disorder.
• suffering from the hematological diseases such as hemolytic anemia.
• cancer patients with lymphoedema at the area of the acupressure points.
• diagnosed combine with other cancers.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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200 participants in 2 patient groups

Acupressure group

Experimental group

Description:

The intervention technique used is ''The electric vibrating massager'', ''SAMPO®'', and patients are taught to apply the strong mode on the 15 specific points,5 min each, 3 times a day from Monday to Friday during chemotherapy course. The intervention follows the points are used to stimulate the hematopoietic function. including Hegu (LI4), Quchi (LI11), Xuehai (SP10); Sanyin-jiao (SP6), Taixi (K3), Zusanli (ST36), Taichong (LV3), Baihui (GV20). Before the study, the trained study nurses teach patients that how to use the technique and stuck adhesive dots label on each specific acupoints.

Treatment:

Device: The Electric vibrating massager,SAMPO®

Control group

No Intervention group

Description:

The patients of the control group are not admitted any acupoints press-related interventions, only take clinical treatment protocol as usual.