The Effect of Adenomoyosis on Pregnancy Outcomes

Tepecik Training and Research Hospital

Status: Unknown

Conditions: Pregnancy Complications; Adenomyosis

Treatments: Other: Non intervention

Study type: Observational

Funder types: Other

Identifiers

NCT04894292

TepecikTRH-001

Details and patient eligibility

About

Adenomyosis can be defined as the settling of endometrial gland cells in the myometrium and deformity in the uterus and the prevalence of adenomyosis is according to the patient population and countries around 20%. There are recent publications reporting that this rate increases up to 50% in women dealing with infertility. In adenomyosis, where uterine morphology is affected, it is not thought that the uterus, which is expected to provide many morphological adaptations during pregnancy, will not be affected. Therefore, in this prospective study, it was planned to investigate the effects of adenomyosis during pregnancy.

For this study the presence of adenomyosis will be questioned by using ultrasonographic morphological uterine limitation (MUSA) in women who apply to the outpatient clinic with suspicion of pregnancy and undergo transvaginal ultrasonography for the diagnosis of pregnancy before sixth gestational week.

Patients will be divided into two groups according to the presence of adenomyosis and pregnancy complications such as preterm labor, premature rupture of membranes, cesarean section rates, preeclampsia, fetal malpresentation and preeclampsia will be compared between the groups.

Enrollment: 150 estimated patients

Sex: Female

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age between 18-35 years
• Being diagnosed before the 6th gestational week
• Having all pregnancy follow-ups and deliveries in our hospital

Exclusion criteria

• Previous uterine surgery
• Multiple pregnancies
• Pregnant women with uterine malformations
• Pregnant women with fetal anomalies
• Those who got pregnant using assisted reproductive technique

Trial design

150 participants in 2 patient groups

Adenomyosis Group

Treatment:

Other: Non intervention

Non-adenomyosis Group

Treatment:

Other: Non intervention