The Effect of Adjunct Vitamin a on Community-Acquired Pneumonia in Southern Iranian Children: a Randomized Clinical Trial (CAP Vitamin A)

Hormozgan University of Medical Sciences

Status

Completed

Conditions

Vitamin a

Community-Acquired Pneumonia

Treatments

Dietary Supplement: Vitamin A

Study type

Interventional

Funder types

Other

Identifiers

NCT06677684

IR.HUMS.REC.1400.113

Details and patient eligibility

About

This randomized clinical trial included 105 children with CAP who were admitted to Bandar Abbas Children's Hospital. Participants were randomly assigned to two groups: a control group receiving standard antibiotic therapy and an intervention group receiving standard antibiotics plus vitamin A (25,000 IU for 2 days). Key data collected included age, sex, duration of hospitalization, treatment duration, and daily Respiratory Index of Severity in Children (RISC) scores.

Full description

Children to present with CAP symptoms

Enrollment

105 patients

Sex

All

Ages

6 months to 12 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

children to present with CAP symptoms, including fever, cough, pulmonary rales, respiratory distress (age-adjusted tachypnea: >50 breaths per minute for infants under 1 year, >40 for ages 1-5 years, and >30 for those over 5 years), and radiographic findings indicative of pneumonia.

Exclusion criteria

underlying immunodeficiency, chronic respiratory conditions, concurrent use of immunosuppressive medications, prior high-dose vitamin A intake, and hospitalizations shorter than 24 hours