The Effect of Aerobic Interval Training on Obstructive Sleep Apnea

Norwegian University of Science and Technology

Status: Completed

Conditions: Obstructive Sleep Apnea Syndrome

Treatments: Behavioral: Control; Behavioral: Aerobic Interval training

Study type: Interventional

Funder types: Other

Identifiers

NCT01215617

2010/1539-5

20101539-2 (Other Identifier)

Details and patient eligibility

About

The purpose of this study is to investigate if 3 months of interval training improves obstructive sleep apnea in obese patients diagnosed with moderate to severe obstructive sleep apnea. The working hypothesis is that 3 months of 3 weekly aerobic interval training sessions improve obstructive sleep apnea and sleep quality in obese patients.

Full description

Obstructive sleep apnea syndrome (OSAS) is characterized by repetitive obstruction and collapse of the upper airway resulting in successive episodes of cessation of or decreased respiratory airflow, causing oxygen desaturation, awakening, loud snoring and daytime sleepiness in patients. Sleep apnea is frequently associated with co-morbidity such as obesity, diabetes, hypertension, the metabolic syndrome and cardiovascular disease. Lack of exercise is associated with OSAS severity, independent of body mass. Participation and motivation to exercise is low in OSAS patients, with less that one third of the patients reporting regular exercise routines. We aim to investigate if aerobic interval training improves OSAS in obese subjects.

Enrollment: 30 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• BMI ≥ 30 kg/M2
• Apne - hypopnea index (AHI) > 10
• No significant comorbidities
• Abel to exercise

Exclusion criteria

• Inability to exercise due to musculoskeletal conditions
• Known ischemic cardiovascular disease
• Drug abuse
• Mental illnesses

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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30 participants in 2 patient groups

Aerobic Interval Training

Experimental group

Description:

Patients randomized to training will meet for supervised aerobic interval training three times per week for 3 months. The interval training session consists of 10 minutes warm up and continues with 4 x 4 minutes of high intensity intervals at 90-95% of maximal heart rate

Treatment:

Behavioral: Aerobic Interval training

Control

Other group

Description:

Patients will receive standard medical treatment at the University Hospital lung department.

Treatment:

Behavioral: Control