The Effect of Alveolar Recruitment Maneuver in Laparoscopic Surgery

Seoul National University

Status: Unknown

Conditions: Postoperative Pulmonary Complication

Treatments: Procedure: Alveolar recruitment maneuver

Study type: Interventional

Funder types: Other

Identifiers

NCT03681236

B1708-415-302

Details and patient eligibility

About

Investigating the effect of alveolar recruitment on the incidence of postoperative pulmonary complication in patients who undergo laparoscopic surgery

Full description

Comparing ventilation with PEEP (positive end expiratory pressure) to ventilation with PEEP and alveolar recruitment, we expect that alveolar recruitment will reduce the incidence of pulmonary complication in patients undergo laparoscopic surgery. Ventilation with only PEEP is generally not enough to reduce postoperative pulmonary complication effectively.

Enrollment: 138 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients, ASA I-II, scheduled to elective laparoscopic surgery

Exclusion criteria

• Chronic lung disease
• Cardiovascular disease
• ASA class ≥ III
• Receiving ventilation therapy or received within 6 months
• Refusal of participation in study or failure in informed consent

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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138 participants in 2 patient groups

No alveolar recruitment maneuver

No Intervention group

Description:

Applying ventilation with tidal volume 6-8mL/kg (ideal body weight) and PEEP 5cmH₂O

Alveolar recruitment maneuver

Active Comparator group

Description:

Applying ventilation with tidal volume 6-8mL/kg (ideal body weight) and PEEP 5cmH₂O. In addition to this, performing alveolar recruitment maneuver at 2 moments: before surgical incision, end of pneumoperitoneum

Treatment:

Procedure: Alveolar recruitment maneuver