The Effect of an Experimental Gel Based on Copaiba Oil Resin in Reducing Post-bleaching Tooth Sensitivity

Universidade Federal do Para

Status: Completed

Conditions: Tooth Bleaching Pain

Treatments: Other: GCO (Experimental copaiba oil resin gel)

Study type: Interventional

Funder types: Other

Identifiers

NCT06066671

UFPara016

Details and patient eligibility

About

This randomized, double-blind clinical trial aimed to evaluate the effect of an experimental gel containing copaiba oil resin in reducing postoperative tooth sensitivity caused by bleaching with 35% hydrogen peroxide. The volunteers of this study were randomized into 3 different groups - GC (placebo); GN (potassium nitrate and sodium fluoride); GCO (copaiba oil resin). The dental elements of the GCO received application of the experimental desensitizing gel on the buccal surfaces of the central incisors, lateral incisors, canines and upper and lower premolars, with a rubber cup in an active way, for 10 minutes. The GC and GN groups also received the application of a placebo gel and a nitrate potassium and sodiun fluoride gel, respectively, under the same conditions described for the experimental gel. Subsequently, all groups underwent in-office bleaching treatment with 35% hydrogen peroxide. Post-bleaching sensitivity was collected through a form composed of the visual analogue scale (VAS). Color measurement was performed at two times: baseline (Ti) and one week after the 3rd bleaching session (Tf).

Enrollment: 75 patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• good oral hygiene
• absence of active caries lesions
• never undergone bleaching therapy
• not present dental hypersensitivity
• don't be a smoker
• don´t be pregnant
• present at least 28 teeth in the oral cavity

Exclusion criteria

• volunteers undergoing orthodontic treatment,
• presence of periodontal disease
• dental cracks or fractures
• restorations and prostheses on anterior teeth
• extensive molar restorations
• gastroesophageal disorders
• severe internal dental darkening
• presence of dentinal exposure in anterior and / or posterior teeth.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

---

75 participants in 3 patient groups, including a placebo group

GCO (Experimental copaiba oil resin gel)

Experimental group

Description:

The GCO group will receive the application of an experimental gel based on copaiba oil resin for post tooth bleaching sensitivity

Treatment:

Other: GCO (Experimental copaiba oil resin gel)

GN (Potassiun nitrate and sodium fluoride gel)

Active Comparator group

Description:

The GN group will receive the application of a potassium and sodium nitrate gel for post tooth bleaching sensitivity

Treatment:

Other: GCO (Experimental copaiba oil resin gel)

GC

Placebo Comparator group

Description:

The GC group will receive the application of a placebo gel for post tooth bleaching sensitivity

Treatment:

Other: GCO (Experimental copaiba oil resin gel)