The Effect Of Anaerobic Exercise On Bone Morphogenetic Protein 9

Ege University

Status: Unknown

Conditions: Healthy; Exercise

Treatments: Other: Physical test; Other: Biochemical tests; Other: Physiological test

Study type: Observational

Funder types: Other

Identifiers

NCT05117437

TDK-2020-22186 (Other Grant/Funding Number)

Details and patient eligibility

About

Bone morphogenetic protein (BMP) 9 from the BMP family has an important role in the remodeling of bone and cartilage. Due to these features, BMP9 can play an important role in especially anaerobic exercise training adaptations. However, the role of anaerobic exercise in these effects is still unclear. The aim of this study is to investigate the role of BMP9 on the effects of acute and chronic anaerobic exercise on bone metabolism markers. Postprandial venous blood samples were taken pre- and post- acute YOYO intermittent recovery test (level 1) in 40 trained male athletes aged 18-35 who did anaerobic sports (such as basketball, volleyball and handball) and 41 sedentary volunteers aged 18-35. Serum BMP9, as markers of bone formation and resorption; alkaline phosphatase (ALP), C-terminal telopeptide of type 1 collagen (CTX1), cartilage oligomeric matrix protein (COMP) and calcium levels were determined. The data to be obtained as a result of our study can give information about the relationship between the skeletal and bone health of the athletes and anaerobic exercise.

Enrollment: 81 patients

Sex: Male

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• being male
• having a body mass index of less than 30 being

Exclusion criteria

• to have some disease or disability
• to regularly use cigarettes and alcohol
• to use any medication or antioxidant substance

Trial design

81 participants in 2 patient groups

Athletic group

Description:

Healthy male athletes who have been doing regular anaerobic sports (such as basketball, volleyball and handball) for at least 3 months

Treatment:

Other: Physical test

Other: Physiological test

Other: Biochemical tests

Control group

Description:

Healthy sedentary (not doing regular sports for at least 3 months) men with age and physical characteristics similar to the athlete group

Treatment:

Other: Physical test

Other: Physiological test

Other: Biochemical tests