The Effect of Auditory Stimuli on Heart Rate Variability (HRV) Among Patients With Acquired Brain Injury (ABI)

Sheba Medical Center

Status: Unknown

Conditions: Acquired Brain Injury

Treatments: Other: Auditory Stimuli

Study type: Interventional

Funder types: Other

Identifiers

NCT01454557

SHEBA-11-8846-OK-CTIL

Details and patient eligibility

About

Heart Rate Variability (HRV) reflects the responsiveness of the autonomic system to an external stimuli. The aim of this system is to maintain homeostasis.The variability implies on the interaction between the sympathetic and the parasympathetic systems to maintain the ongoing changes of the autonomic system. Following Acquired Brain Injury (ABI), there can be a damage to the Central Nervous System (CNS) function. The damages described in the literature are cognitive, motor and behavioural function, while there is less relation to the autonomic system. The autonomic system can influence the ability of patient with ABI to participate in the rehabilitation program. The aim of this work is to investigate the activity of the autonomic system activity as manifested by HRV among patients with ABI in different conditions: resting, during activity and while listening to different auditory stimuli.

Enrollment: 80 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 2-4 months from acceptance to rehabilitation medical stable

Exclusion criteria

• medical unstable a significant hearing deficit premorbid neurological or mental condition

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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80 participants in 2 patient groups

Acquired Brain Injury

Experimental group

Description:

auditory stimuli for ABI group

Treatment:

Other: Auditory Stimuli

Controls

Experimental group

Description:

Auditory stimuli for control group

Treatment:

Other: Auditory Stimuli