The Effect of Automated Electronic Alert for Acute Kidney Injury on the Outcomes of Hospitalized Patients

Nanjing Medical University

Status: Completed

Conditions: Early Diagnosis; Acute Kidney Injury; Outcomes

Treatments: Device: AKI alert; Other: Usual care

Study type: Interventional

Funder types: Other

Identifiers

NCT03736304

2018-SR-180

Details and patient eligibility

About

Acute kidney injury (AKI) is a common disease, but diagnosis is usually delayed or missed in hospitalized patients. The automated electronic alert for AKI may help to improve the outcomes of these patients through identifying all cases of AKI early. Therefore, the investigators conduct a randomly controlled study to test whether automated electronic alert for AKI could improve the outcomes of hospitalized patients.

Full description

Acute kidney injury (AKI) is a common disease, but diagnosis is usually delayed or missed in hospitalized patients. The automated electronic alert for AKI may help to improve the outcomes of these patients through identifying all cases of AKI early. Therefore, the investigators conduct a randomly controlled study to test whether automated electronic alert for AKI could improve the outcomes of hospitalized patients.

The patients were randomly divided into two groups:

Usual care : patients will receive standard clinical care by the primary physicians AKI alert : an AKI alert will be sent to the doctor in charge. The team of kidney experts would give a suggestion if the doctor in charge need a renal consultation.

Enrollment: 4,536 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Hospitalized adult patients with an Alert for AKI(based on KDIGO guidelines)

Exclusion criteria

• Patients already having eGFR<15ml/min/1.73m2 or receiving renal replacement therapy for AKI at the time of alert.
• Patients already having a AKI before admission.

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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4,536 participants in 2 patient groups, including a placebo group

Usual care

Placebo Comparator group

Description:

Patients will receive standard clinical care by the doctor in charge.

Treatment:

Other: Usual care

AKI alert

Experimental group

Description:

An AKI alert will send to the the doctor in charge. The team of nephrologists would give suggestions if the doctor in charge need a renal consultation.

Treatment:

Device: AKI alert