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The Effect of Bariatric Surgery to Central Sensitization

B

Bursa Yüksek İhtisas Education and Research Hospital

Status

Unknown

Conditions

Central Sensitization
Bariatric Surgery

Treatments

Procedure: Bariatric surgery

Study type

Observational

Funder types

Other

Identifiers

NCT03460691
2011-KAEK-2017-19/20

Details and patient eligibility

About

Nowadays obesity is emerging as a very common health problem. It has been shown in various studies that obesity may be an important risk factor for the onset and progression of knee osteoarthritis (OA). The aim of this study is to determine the effects of bariatric surgery on knee pain, loss of function, quality of life and central sensitization.

Full description

Weight loss in patients with knee OA reduces pain and provides functional improvement. It has been shown that bariatric surgery combined with diet and exercise changes have positive effects on weight loss, knee pain and function.

Neuropathic pain is a disease that affects the somatosensory system or pain that results in a lesion. It has been reported that neuropathic pain is more frequently seen in patients with high body mass index.

The hyperreactivity of the central nervous system (CNS) plays an important role in the chronic pain of OA patients. It has been shown that CNS becomes hypersensitive in people with chronic OA pain and central sensitization phenomenon plays an important role in pain complaints reported by these patients.

The aim of this study is to determine the effects of bariatric surgery on knee pain, loss of function, quality of life and central sensitization.

Enrollment

50 estimated patients

Sex

All

Ages

18 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patients decided to undergo bariatric surgery
  • Patients with knee pain more than 3 months.

Exclusion criteria

  • Patients with mental impairment,
  • Patients with inflammatory rheumatic disease,
  • Patients who had previously undergone knee surgery

Trial design

50 participants in 1 patient group

Group 1
Description:
Group 1:patients who will undergo the bariatric surgery
Treatment:
Procedure: Bariatric surgery

Trial contacts and locations

0

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Central trial contact

Burcu Metin Ökmen, M.D.

Data sourced from clinicaltrials.gov

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