The Effect of Black Currant on Postprandial Glucose Metabolism (MAQUA)

University of Eastern Finland

Status: Completed

Conditions: Prediabetic State; Postprandial Hyperglycemia

Treatments: Other: Black currant-quinoa product; Other: Quinoa base; Other: Black currant

Study type: Interventional

Funder types: Other

Identifiers

NCT04150926

894/2019

Details and patient eligibility

About

The study examines the effect of black currant on glucose and insulin concentrations after a meal. In addition, the cytokine and free fatty acids levels are of interest.

Full description

The study examines the effect of black currant on glucose and insulin concentrations after a meal.

Healthy (n= 30) volunteers are recruited to participate in four consecutive visits in the research laboratory, when four meals are served in randomised order. Meals are: black currant puree, black currant and quinoa based snack, quinoa base and liquid containing glucose, fructose and sucrose. The meals contain the same amount of carbohydrates.

In addition to glucose and insulin concentration, cytokine and free fatty acid concentrations are measured after each meal.

Enrollment: 26 patients

Sex: All

Ages: 25 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• age: 25-65 years
• BMI: 20-28 kg/m2
• Perceived health status: Good

Exclusion criteria

• fasting glucose: > 7.0 mmol/l
• LDL-cholesterol: > 3.0 mmol/l
• total cholesterol: > 6.5 mmol/l
• blood pressure : > 160/100 mmHg
• weight change of > 5% during previous 6 months or active weightreduction
• no serious chronic diseases
• one exception of the exclusion criteria maybe accepted after the MD consideration

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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26 participants in 4 patient groups

Black currant puree

Experimental group

Description:

Black currant puree

Treatment:

Other: Black currant

Black currant-quinoa product

Active Comparator group

Description:

Black currant-quinoa product

Treatment:

Other: Black currant-quinoa product

Quinoa base

Active Comparator group

Description:

Quinoa base is used for the black currant-quinoa product.

Treatment:

Other: Quinoa base

Liquid with glucose, fructose and sucrose

No Intervention group

Description:

Liquid with glucose, fructose and sucrose