The Effect of Cataract Extraction on the Contractility of Ciliary Muscle

Samsung Medical Center

Status: Unknown

Conditions: Cataract; Presbyopia

Treatments: Other: UBM with pilocarpine in presbyopia

Study type: Interventional

Funder types: Other

Identifiers

NCT00624039

CB2006

Details and patient eligibility

About

The purpose of this study is to investigate the changes in the pilocarpine-induced ciliary body movement before and after cataract extraction in order to determine the effect of lens sclerosis on the ciliary muscle contractility.

Full description

The functional changes in the ciliary body in presbyopia are not only important in a study of the mechanism for presbyopia but are also a key to various procedures or devices used to restore accommodation. Therefore, it is becoming increasingly important to quantify the in vivo accommodative changes in the aging ciliary muscle with and without a lens. We are going to evaluate the changes in the pilocarpine-induced contractility of the ciliary muscle in eyes with presbyopia before and after cataract extraction using ultrasound biomicroscopy (UBM).UBM will be performed with and without instilling 2 % pilocarpine, as well as before and 2 months after cataract extraction. Images of the ciliary body will be compared visually using Adobe Photoshop 7.0.

Enrollment: 15 patients

Sex: All

Ages: 55+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age : same or more than 55 years
• Patients with senile cataract who are going to get cataract surgery

Exclusion criteria

• Age : less than 55 years
• Previous ocular disease other than cataract.

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: Double Blind

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15 participants in 1 patient group

1

Other group

Description:

ultrasound biomicrocopic examinations and pilocarpine instillation

Treatment:

Other: UBM with pilocarpine in presbyopia