The Effect of Centella Asiatica Cream on Scar Tenderness Who Underwent Open Carpal Tunnel Release Surgery

Mustafa Balevi,MD

Status and phase: Completed; Early Phase 1

Conditions: To Prevent Scar Formation for Patients Underwent Surgery

Treatments: Drug: undefinedCentella Asiatica Extract

Study type: Interventional

Funder types: Other

Identifiers

NCT05017467

B.10.4.ISM.4.42.00.14-8271

Details and patient eligibility

About

The centella asiatica cream applied to the wrist after the CTR surgery was found to be beneficial in preventing the scar tenderness in the thenar and hypothenar regions of the hand.

Full description

Aim: This study was performed to evaluate the efficacy of centella asiatica extract in a cream preparation for the prevention of scar tenderness formation in patients who underwent conventional open carpal tunnel release surgery.

Enrollment: 280 patients

Sex: All

Ages: 19 to 90 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: patient underwent open carpal tunnel release surgery -

Exclusion Criteria:before hand surgery and recurrent carpal tunnel release surgery.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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280 participants in 2 patient groups

vss

Experimental group

Description:

Vancouver Scar Scale (VSS) at the one, three and 6 months after surgery

Treatment:

Drug: undefinedCentella Asiatica Extract

QuickDASH , VAS

Experimental group

Description:

, Quick Disabilities of Arm Shoulder and Hand functional score (QuickDASH) and Visual Analogue Scale (VAS) test was used to determine overall hand function, activities of daily living, work performance, pain, aesthetics, and satisfaction with hand function

Treatment:

Drug: undefinedCentella Asiatica Extract