The Effect of Chamomile on Healing After Tooth Extraction

reyhansaglam

Status: Completed

Conditions: Tooth Extraction Status Nos

Treatments: Other: Physiological serum mouthwash; Other: Chamomile mouthwash; Other: Chlorhexidine mouthwash

Study type: Interventional

Funder types: Other

Identifiers

NCT06770166

10840098-604.01.01-21824

Details and patient eligibility

About

After impacted wisdom tooth extraction, patients frequently complain of pain, edema, and limited mouth opening. After the procedure, patients are routinely recommended to use chlorhexidine and physiological serum-based mouthwashes. The antibacterial and anti-inflammatory effects of warm chamomile tea have been reported in the literature. In addition, the neuroprotective, antiallergic, antioxidant, antiseptic and spasmolytic properties of chamomile have been reported. The aim was to compare the effects of these gargles in terms of pain, mouth opening, burning sensation in the mouth, edema, and discoloration of the tongue and teeth.

Full description

The study was planned to be applied to 120 patients, 40 in each group. In the ASA 1 group, the mouth opening of the patients was recorded before the tooth extraction procedure. Impacted teeth were extracted using Ultracain D-S Forte (Articaine HCl: 40mg/ml, Epinephrine HCl: 0.012 mg/ml) as a local anesthetic. Dental units were prepared under sterile conditions. The patients were covered with a sterile drape. The lower wisdom tooth was extracted with open (surgical) extraction. The mucoperisoteal flap was lifted with a number 15 surgical scalpel, and the tooth was extracted using round and fissure-tipped steel burs with a handpiece. After tooth extraction, if there was granulation tissue in the extraction socket, it was curetted and irrigated with physiological serum [sodium chloride: 0.009 g/ml, sodium 154 (mEq/I), chloride 154 (mEq/I)]. After bleeding control, patients were given written and verbal postoperative advice. Antibiotics and analgesics were prescribed to patients, chlorhexidine gargle was recommended to 30 patients, saline gargle to 30 patients, and chamomile tea gargle to 30 patients. Patients were given VAS pain scores, numbered 0-10, to record for 7 days after extraction. Patients were called back to the clinic on the 2nd and 7th days after tooth extraction to assess pain, burning sensation and color change in the tongue, mouth opening, and edema. Sutures were removed on the 7th postoperative day.

Enrollment: 120 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. American Society of Anesthesiologists (ASA) physical status I patients,
2. did not have the medical history of being allergic to local anesthesia
3. did not have the medical history of being allergic to CHX,
4. did not have acute infection at the tooth area
5. absence of any pathology at the area.

Exclusion criteria

1. Participants with medically compromised condition,
2. pregnant females
3. smokers

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: Double Blind

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120 participants in 3 patient groups

physiological serum mouthwash group (control group)

Active Comparator group

Description:

After extraction, 40 patients were given saline mouthwash to use for 7 days.

Treatment:

Other: Physiological serum mouthwash

chlorhexidine mouthwash group

Active Comparator group

Description:

After extraction, 40 patients were given chlorhexidine mouthwash to use for 7 days.

Treatment:

Other: Chlorhexidine mouthwash

chamomile mouthwash group

Active Comparator group

Description:

After extraction, 40 patients were given chamomile mouthwash to use for 7 days.

Treatment:

Other: Chamomile mouthwash