The Effect of Chewing the Tapioca Pearls in Bubble Tea Drinks

Gadjah Mada University

Status: Completed

Conditions: Saliva

Treatments: Other: chewing tapioca pearls in bubble tea drinks; Other: drink tea without chewing tapioca pearls

Study type: Interventional

Funder types: Other

Identifiers

NCT04670341

FKGUGM1

Details and patient eligibility

About

Bubble tea drinks contain tea and tapioca pearls. Chewing tapioca pearls in bubble tea drinks may increase salivary components. Because of its proteins, inorganic components, and enzymes, saliva plays an important role in the body's defense against bacteria and viruses. This study aims to analyze the effect of chewing the tapioca pearls in bubble tea drinks on salivary C-reactive protein (CRP) and calcium (Ca) levels.

Full description

Sixty saliva samples were collected from 15 subjects. The inclusion criterion was 18-25 years of age. The exclusion criteria were receiving medication, using dentures, a history of dry mouth, smoking and systemic disease. In the first week of the experiment, subjects drank bubble tea as the intervention group. In the second week, the same subjects drank tea without pearls as the control group. Each subject drank the bubble tea for 5 minutes per day over 3 days. Saliva samples were collected on the first day before bubble tea consumption (pretest) and on the third day after tea consumption (posttest). Saliva collection was performed in the morning (09:00 a.m.-12:00 p.m.) for 1 minute. Salivary CRP levels were measured using an ELISA kit, and Ca levels were determined using a test kit.

Enrollment: 15 patients

Sex: All

Ages: 18 to 25 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• good Oral Hygiene Index-Simplified (OHI-S) score

Exclusion criteria

• taking medication
• a history of dry mouth
• smoking
• systemic disease

Trial design

Primary purpose: Basic Science

Allocation: Non-Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

---

15 participants in 2 patient groups, including a placebo group

chewing tapioca pearls in the bubble tea drinks

Experimental group

Description:

In the first week, the subjects drink as much as 100 ml of bubble tea over a span of 5 minutes once a day for 3 days

Treatment:

Other: chewing tapioca pearls in bubble tea drinks

drink tea without chewing tapioca pearls

Placebo Comparator group

Description:

In the second week, the subjects drink tea without tapioca pearls as much as 100 ml for 5 minutes per day for 3 days.

Treatment:

Other: drink tea without chewing tapioca pearls