The Effect of Cinnamon on HbA1c Among Adolescents With Type I Diabetes

Dartmouth Health

Status and phase: Completed; Phase 3; Phase 2

Conditions: Type 1 Diabetes Mellitus

Treatments: Drug: cinnamon

Study type: Interventional

Funder types: Other

Identifiers

NCT00371800

17648

Details and patient eligibility

About

the purpose of this study is to determine if cinnamon improves glucose control among adolescents with type 1 diabetes mellitus.

Full description

Widespread achievement of glucose control remains an elusive goal for adolescents with Type 1 diabetes. Previous research has suggested that cinnamon may be effective at improving glucose control in type 2 diabetes. To date, no research has investigated the effect of cinnamon on type 1 diabetics. If the addition of a simple, natural, pill to a standard insulin regimen can significantly improve glucose control, the clinical implications would be substantial.

Comparison: Using a prospective, double-blind, placebo-controlled design, 72 adolescent type I diabetics were treated with cinnamon (1 gram/day) or an equivalent appearing placebo for 90 days. HbA1c, total daily insulin intake, and adverse events were recorded and compared between groups.

Sex: All

Ages: 13 to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Diagnosis of Type 1 diabetes for > 18 months prior to enrollment,
2. Age 13-18 years at the time of enrollment
3. Presenting to the clinic for routine care,
4. No hospital admissions for medical or psychiatric reasons in the 12 months prior to enrollment,
5. Accessible by phone,
6. Not pregnant.

Exclusion criteria

(1) Pregnant

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind