The Effect of Clonidine in Glycemia During Coronary Artery Bypass Graft With Cardiopulmonary By-pass

Federal University of Juiz de Fora

Status and phase: Completed; Phase 4

Conditions: Sedation During Pre-anesthetic Medication; Glycemia During Coronary Artery Bypass Graft

Treatments: Drug: Clonidine; Drug: Ringer lactato

Study type: Interventional

Funder types: Other

Identifiers

NCT01619436

0279/03.05.2010

Details and patient eligibility

About

The purpose of this study is the randomized blind research of the assessment of the different levels of glycemia during Coronary Artery Bypass Graft (CABG) with cardiopulmonary by-pass (CPB) between clonidine and placebo. As clonidine decrease the inflammatory response during cardiac surgery, the investigators would like to know if the glycemia levels in clondine group will be lower than placebo group.

Enrollment: 46 patients

Sex: All

Ages: 45 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• elective CABG EF > 40% Sinus ritmy

Exclusion criteria

• precordialgia emergency surgery combinated surgery not agreement

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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46 participants in 2 patient groups, including a placebo group

clonidine

Active Comparator group

Description:

clonidine 2 mg/kg IV

Treatment:

Drug: Clonidine

ringer lactato 1 ml

Placebo Comparator group

Description:

Ringer lactato 1 ml IV as Placebo

Treatment:

Drug: Ringer lactato