The Effect of Coffee After Resection of Small Bowel

Mount Carmel Health System

Status: Completed

Conditions: Postoperative Ileus

Treatments: Dietary Supplement: Coffee; Other: Water

Study type: Interventional

Funder types: Other

Identifiers

NCT03143621

Coffee Small Bowel

Details and patient eligibility

About

Post-operative ileus ("post-op ileus") is a condition which can occur after surgery. This means that the bowels stop working correctly and food and liquids will not pass through in the normal manner. Post-op ileus can be uncomfortable and require a longer hospital stay until the bowels begin to function correctly again. Currently there are no effective methods for preventing post-op ileus. Some studies suggest there is a benefit from drinking coffee following colon or gynecological cancer surgeries with very little risk. However, the effects of coffee following small bowel surgery have not been studied. This randomized, controlled trial will compare the outcomes of patients who receive coffee during their hospital stay after small bowel surgery to similar patients who receive warm water. About 60 patients will be in each group. The main outcomes are time until the nasogastric tube is removed and length of hospital stay.

Enrollment: 79 patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients undergoing small bowel resection. Can be elective, urgent or emergent.

Exclusion criteria

• Patient with atrial fibrillation who is considered a non-coffee drinker (drinks coffee less than 3 days per week over the last 4 weeks)
• Patients undergoing colon resection without removal of any portion of small bowel.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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79 participants in 2 patient groups, including a placebo group

Coffee

Experimental group

Description:

100 cc's of coffee administered three times per day until return to bowel function has been established.

Treatment:

Dietary Supplement: Coffee

Water

Placebo Comparator group

Description:

100 cc's of warm water administered three times per day until return to bowel function has been established.

Treatment:

Other: Water