The Effect of Consuming a guaraná and Vitamin/Mineral Complex Pre-exercise on Affect, Exertion, Metabolism and Cognition

Northumbria University

Status and phase: Completed; Phase 4

Conditions: Affect and Exertion During and Post-exercise

Treatments: Dietary Supplement: Placebo; Dietary Supplement: Berocca Boost

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT01929694

9B2

Details and patient eligibility

About

Consuming a guaraná and vitamin and mineral complex can improve mental fatigue and cognitive function at rest; guaraná also contains caffeine, which can reduce perceived exertion and increase fat burning during exercise. The purpose of this study is to test whether consuming a guaraná and vitamin and mineral product before exercise influences affect (mood), physical exertion and fat burning during exercise and mental fatigue, cognitive performance and affect post-exercise.

Enrollment: 40 patients

Sex: Male

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Individuals must be:

• Healthy
• Male
• Aged between 18 and 35years
• Habitually active (exercising at least twice a week)
• Able to run at a moderate pace for 30 minutes non-stop on a treadmill

Exclusion criteria

Individuals will not be eligible to take part in this study if they:

• have a history of neurological or psychiatric diseases excluding anxiety or depression
• have a current diagnosis of depression or anxiety
• have a history of significant head trauma, metabolic, endocrine or cardiac disorders
• have smoked within the last 3 months,
• have high blood pressure >140/90mmHg
• consume > 500 mg caffeine per day from all dietary sources
• have adverse reactions to caffeine containing products (i.e. tea, coffee, energy drinks, cola, Pepsi)
• are currently taking any pharmaceuticals
• have habitual taken dietary supplements within the last 4 weeks (defined as ≥3 consecutive days or ≥4 days in total per week)
• have current or history of drug or alcohol abuse
• have participated in another clinical trial within 30 days prior to screening
• have any condition which may interfere with your ability to perform assessments
• have any history of hypersensitivity to the investigational product or its active or inactive constituents or any food allergy or intolerance

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Quadruple Blind

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40 participants in 2 patient groups, including a placebo group

Berocca Boost

Active Comparator group

Description:

Guarana and vitamin and mineral complex, one tablet dissolved in 250ml water taken once.

Treatment:

Dietary Supplement: Berocca Boost

Placebo

Placebo Comparator group

Description:

Matched placebo tablet, one tablet dissolved in 250ml water taken once.

Treatment:

Dietary Supplement: Placebo