The Effect of Consuming Enzymes and Prebiotics on Body Composition and Blood Biochemical Index

TCI

Status: Completed

Conditions: Gut Microbiota

Treatments: Other: weight loss program kit with A. muciniphila prebiotics; Other: weight loss program kit; Other: normal diet

Study type: Interventional

Funder types: Industry

Identifiers

NCT04303481

19-062-A

Details and patient eligibility

About

To assess the effects of consuming enzymes and prebiotics on improvement of weight loss and biochemical parameters

Enrollment: 88 patients

Sex: All

Ages: 20 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Male or female aged between 20 and 50 years old
• Body mass index (BMI) ≥ 22 (kg/m^2) or body fat mass: male > 25%, female > 30%
• Prohibitions on other nutritional supplements (probiotics and prebiotics) before two weeks of the study
• Abidance by the similar diet and exercise habits over the study.

Exclusion criteria

• Pregnant or breastfeeding woman
• Menopausal woman
• Diabetes mellitus
• Implementation in weight loss programs before a half year of this study
• Metabolic disorders
• Kidney diseases
• Liver diseases
• Cardiovascular diseases
• Nervous system diseases
• Gastrointestinal diseases
• Heavy drinking or constant drug use.

Trial design

Primary purpose: Other

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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88 participants in 3 patient groups

normal diet

Other group

Treatment:

Other: normal diet

weight loss program kit

Experimental group

Treatment:

Other: weight loss program kit

weight loss program kit with A. muciniphila prebiotics

Experimental group

Treatment:

Other: weight loss program kit with A. muciniphila prebiotics