The Effect of CoQ10 Administration on Hemodialysis Patients

University of Shizuoka

Status and phase: Completed; Phase 4

Conditions: Hemodialysis; Chronic Renal Failure

Treatments: Drug: Coenzyme Q10 (drug)

Study type: Interventional

Funder types: Other

Identifiers

NCT00307996

CT2006001

Details and patient eligibility

About

The purpose of this study is to examine whether CoQ10 administration is effective as an antioxidant in hemodialysis patients.

Full description

Oxidative stress has been recognized as a potential risk factor for such complications as atherosclerosis in hemodialysis patients. This study investigates whether CoQ10 administration is effective for protecting oxidative stress in hemodialysis patients. The subjects were recruited from day-time hemodialysis patients in Iwata City Hospital. 100 mg CoQ10 was administered every HD for 6 months. Several oxidative and antioxidative markers were measured in plasma at pre, 1, 3, 6 months and after washout.

Sex: All

Ages: Under 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• hemodialysis for at least 6 months

Exclusion criteria

• none

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)