The Effect of Curcumin Supplementation on Recovery From Exercise-induced Muscle Damage

St Mary's University College

Status: Unknown

Conditions: Exercise Induced Muscle Damage

Treatments: Dietary Supplement: Curcumin

Study type: Interventional

Funder types: Other

Identifiers

NCT05346211

ASE22HELCON

Details and patient eligibility

About

Recent evidence suggests that curcumin supplementation may reduce muscle inflammation, oxidative markers, and muscle damage. The most favourable dosage to elicit these ergogenic effects are yet to be established; both 750mg & 1500mg has been shown to be effective. Curcumin supplementation has been ingested in numerous different ways however, no previous research to date has used curcumin in a hydrolysed (drinkable) format. The aim of this study is to investigate whether hydrolysed curcumin can reduce indices of muscle damage and improve recovery, whilst also examining a potential dose-response effect.

Enrollment: 36 estimated patients

Sex: All

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Inclusion criteria are as follows:

• between the age of 18-35
• non-smoker
• no previous history of cardiovascular, respiratory, or neurological problems
• not taking anticoagulant medication
• injury-free in the 3 months prior to scheduled participation in the study

Exclusion criteria

Exclusion criteria include:

• hypertension (<140/80)
• any blood diseases or clotting issues,
• injury, or previous injury in <3 months

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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36 participants in 3 patient groups

Curcumin Single

Experimental group

Description:

The Single dose group will consume 1 placebo sachet and one curcumin sachet per day. Curcumin supplementation will be from YourZooki, the supplement in question is commercially offered to the public in a tangerine flavour. The sachets will be in 750mg hydrolysed format. The placebo is a sachet containing the same ingredients mentioned above minus the curcumin. The sachets will be in 750mg hydrolysed format. Supplementation will be administered and commence 48-hours prior to the first testing day and will be consumed twice a day (8am \& 8pm).

Treatment:

Dietary Supplement: Curcumin

Curcumin Double

Experimental group

Description:

The double dose group will consume two sachets per day of curcumin. Curcumin supplementation will be from YourZooki, the supplement in question is commercially offered to the public in a tangerine flavour. The sachets will be in 750mg hydrolysed format. Supplementation will be administered and commence 48-hours prior to the first testing day and will be consumed twice a day (8am \& 8pm).

Treatment:

Dietary Supplement: Curcumin

Placebo

No Intervention group

Description:

Placebo sachets containing the same ingredients mentioned above minus the curcumin. The sachets will be in 750mg hydrolysed format. Participants will consume two sachets per day. Supplementation will be administered and commence 48-hours prior to the first testing day and will be consumed twice a day (8am \& 8pm).