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The Effect of Dark Chocolate Consumption on Blood Parameters in Healthy Adult Individuals

E

Eastern Mediterranean University

Status

Completed

Conditions

Cardiovascular Diseases

Treatments

Other: Dark Chocolate

Study type

Interventional

Funder types

Other

Identifiers

NCT05290012
ETK00-2020-0283

Details and patient eligibility

About

In healthy individuals, the effect of regular dark chocolate consumption for 4 weeks on blood lipid parameters such as; total cholesterol, LDL cholesterol, HDL cholesterol and triglyceride levels, in addition to fasting blood glucose, HbA1c, CRP levels and blood pressure was investigated.

Full description

Recent studies have shown that dark chocolate consumption may have a positive effect on cardiovascular risk markers.The aim of this study is to investigate the effect of regular consumption of dark chocolate (36 g/day) on biochemical blood parameters in healthy individuals. A total of 37 healthy individuals completed the study conducted in this direction. Participants were randomly divided into two groups as dark chocolate group (n=17) and control group (n=20). While the dark chocolate group consumed 36 g/day (400 mg/day flavanol) dark chocolate for 4 weeks, the control group did not receive any intervention. At the end of the study, the anthropometric measurements of the individuals were evaluated. Blood lipid profile, fasting blood glucose, HbA1c, CRP levels, systolic blood pressure and diastolic blood pressure measurements were investigated.

Enrollment

37 patients

Sex

All

Ages

19 to 50 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • BMI < 30 kg/m2
  • Systolic blood pressure <140 mmHg and/or diastolic blood pressure <90 mmHg

Exclusion criteria

  • Individuals with any diagnosed chronic or acute illness
  • Individuals diagnosed or in contact with Covid-19
  • Individuals with allergies to cocoa/chocolate products
  • Individuals in the process of losing weight
  • Individuals with smoking and alcohol consumption
  • Individuals taking medication or vitamin/mineral supplements
  • Individuals doing heavy physical activity
  • Individuals who regularly consume cocoa/chocolate products for the last 1 month (> 3 days a week)
  • Pregnant or lactating women were excluded from the study.

Trial design

Primary purpose

Prevention

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

37 participants in 2 patient groups

Dark Chocolate
Experimental group
Description:
Participants consumed 18 grams of dark chocolate (36 g/day, 400 mg/day of flavanols) twice daily.
Treatment:
Other: Dark Chocolate
Control
No Intervention group
Description:
No intervention was made

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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