the Effect of Dexmedetomidine and Licodaine on Acute Postoperative Pain in Gynecological Laparoscopy

The Catholic University of Korea

Status: Withdrawn

Conditions: Gynecologic Disease

Treatments: Drug: Dexmedetomidine Hydrochloride; Drug: Lidocaine Hydrochloride; Drug: Remifentanil Hydrochloride

Study type: Interventional

Funder types: Other

Identifiers

NCT04906889

dexmedetomidine-lidocaine

Details and patient eligibility

About

The aim of this study is to investigate the effect of opioid-free anesthesia using dexmedetomidine and lidocaine instead of remifentanil infusion, on the acute postoperative pain after the gynecological laparoscopy

Full description

This study is performed to investigate the effect of dexmedetomidine and lidocaine the postopeative pain, shivering, nausea and vomiting after the gynecological laparoscopy.

Sex: Female

Ages: 20 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients scheduled for elective gynecological laparoscopy

Exclusion criteria

• emergent surgery
• cancer surgery
• chronic pain requiring pain killers
• psychiatric disease
• preoperative bradycardia (HR < 50 bpm)
• allergies
• pregnancy or breast feeding

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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0 participants in 2 patient groups

dexmedetomidine-lidocaine

Experimental group

Description:

The study group receives the dexmedetomidine and lidocaine infusion with general anesthesia for gynecological laparoscopy.

Treatment:

Drug: Lidocaine Hydrochloride

Drug: Dexmedetomidine Hydrochloride

remifentanil

Active Comparator group

Description:

The control group receives the remifentanil infusion with general anesthesia for gynecological laparoscopy

Treatment:

Drug: Remifentanil Hydrochloride