the Effect of Dexmedetomidine in Coracoid Approach Brachial Plexus Block

The First Hospital of Qinhuangdao

Status and phase: Completed; Phase 4

Conditions: Injury of Upper Limb

Treatments: Drug: ropivacaine; Drug: ropivacaine mixed with dexmedetomidine

Study type: Interventional

Funder types: Other

Identifiers

NCT02961361

Dex

Details and patient eligibility

About

Dexmedetomidine is an α-2 adrenoreceptor agonist and has been extensively used through intravenous infusion，in order to improved the quality of block in regional anesthesia. In this prospective, randomized study, the authors focus on the effect of dexmedetomidine mixed with ropivacaine in coracoid approach brachial plexus block.

Enrollment: 60 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. American Society of Anesthesiologists (ASA) physical status I or II;
2. Aged 18-60 years;
3. The elbow, forearm, wrist or hand surgery

Exclusion criteria

1. History of allergy to local anesthetics;
2. Coagulation dysfunction, neuromuscular disease or local infection;
3. The operation time is longer than the local anesthetics effective time.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 2 patient groups

Group Control

Experimental group

Description:

40 ml 0.375% ropivacaine was injected after Locating brachial plexus.

Treatment:

Drug: ropivacaine

Group Dexmedetomidine

Experimental group

Description:

40 ml 0.375% ropivacaine mixed with dexmedetomidine was injected after Locating brachial plexus.

Treatment:

Drug: ropivacaine mixed with dexmedetomidine