The Effect of Dexmedetomidine in the Management of Pain After Uterine Artery Embolization

Yonsei University

Status: Completed

Conditions: Pain Control

Treatments: Drug: Dexmedetomidine; Drug: Normal saline 0.9%

Study type: Interventional

Funder types: Other

Identifiers

NCT01578174

4-2011-0928

Details and patient eligibility

About

The investigators examined the effect of dexmedetomidine in the management of pain after uterine artery embolization.

Full description

Leiomyoma are the most common female reproductive tract tumors. Uterine artery embolization(UAE) is a minimally invasive treatment alternative to hysterectomy and myomectomy. However, post-procedural pain control after UAE remains a major problem. Therefore, the aim of study is to evaluate the efficacy of dexmedetomidine in pain control after UAE.

Enrollment: 66 patients

Sex: Female

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age ≥ 20,
• ASA class I and II

Exclusion criteria

• bradycardia (< 45 bpm)
• heart block
• liver failure
• renal failure
• uncontrolled hypertension
• body mass index ≥ 30 kg/m2

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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66 participants in 2 patient groups, including a placebo group

Control

Placebo Comparator group

Treatment:

Drug: Normal saline 0.9%

Dexmedetomidine

Active Comparator group

Treatment:

Drug: Dexmedetomidine