The Effect of Dexmedetomidine on Postoperative Analgesia

Seoul National University

Status and phase: Completed; Phase 4

Conditions: Colon Cancer, Rectal Cancer

Treatments: Drug: Fentanyl; Drug: Dexmedetomidine

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT01373021

sunrud1129

Details and patient eligibility

About

The purpose of this study is to determine whether additional Dexmedetomidine to patient controlled analgesia can reduce fentanyl consumption.

Enrollment: 95 patients

Sex: All

Ages: 20 to 74 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Elective surgery for colon cancer

Exclusion criteria

• Liver disease
• Kidney disease
• Allergy for study drugs
• Inability to receive patient controlled analgesia

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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95 participants in 2 patient groups, including a placebo group

F

Placebo Comparator group

Description:

Fentanyl+Normal saline

Treatment:

Drug: Fentanyl

D

Experimental group

Description:

Fentanyl+Dexmedetomidine

Treatment:

Drug: Dexmedetomidine