The Effect of Dexmedetomidine on the Emergence Agitation in Nasal Surgery

Yonsei University

Status: Completed

Conditions: Airway Extubation

Treatments: Drug: Normal saline 0.9%; Drug: Dexmedetomidine

Study type: Interventional

Funder types: Other

Identifiers

NCT01513772

4-2011-0742

Details and patient eligibility

About

The investigators examined the effect of dexmedetomidine on the emergence agitation and postoperative quality of recovery in nasal surgery

Full description

Emergence agitation during the immediate postanesthetic period is common. It may lead to serious consequences for the patient, such as injury, increased pain, hemorrhage, self-extubation, and removal of catheters. Emergence agitation is common in ENT surgery. The aim of this study is to evaluate the effect of dexmedetomidine on the emergence agitation and postoperative quality of recovery in adult patients undergoing nasal surgery.

Enrollment: 100 patients

Sex: All

Ages: 20 to 59 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age ≥ 20,
• ASA class I and II,
• nasal surgery

Exclusion criteria

• bradycardia (< 45 bpm),
• heart block,
• liver failure,
• renal failure,
• uncontrolled hypertension,
• body mass index ≥ 30 kg/m2

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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100 participants in 2 patient groups, including a placebo group

Control

Placebo Comparator group

Treatment:

Drug: Normal saline 0.9%

Dexmedetomidine

Active Comparator group

Treatment:

Drug: Dexmedetomidine