The Effect of Diclofenac Potassium Insitu Gel Vs Calcium Hydroxide as Intra-canal Medications on Post-operative Pain and Anti-bacterial Effect

Cairo University (CU)

Status

Unknown

Conditions

Post Operative Pain

Treatments

Drug: Diclofenac Potassium

Study type

Interventional

Funder types

Other

Identifiers

NCT04622488

ENDO 3-7-2

Details and patient eligibility

About

The aim of this study is to clinically compare the post-operative pain level and antibacterial effect when using the Diclofenac Potassium Insitu gel versus calcium hydroxide as an intra- canal medication in patients with apical periodontitis.

Enrollment

44 estimated patients

Sex

All

Ages

18 to 45 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Age between 18-45 years old.
Males/Females.
Lower permanent premolars with: Non-Vital pulps. Sensitive to percussion. Negative response to cold pulp tester (ethyl chloride spray1). Apical periodontitis
Systemically healthy patients (ASA I or II).

Exclusion criteria

Medically compromised patients having significant systemic disorders. (ASA III or IV).
- History of intolerance to NSAIDS.
- Patients with two or more adjacent teeth requiring endodontic treatment.
- Teeth with :
Association with swelling or fistulous tract.
Acute or chronic peri-apical abscess. Mobility Grade II or III.
Pocket depth more than 5mm.
Previous root canal therapy.
Non-restorability
Patients with a contraindication for the use of DFK or those known to be allergic to any of the study medications.eg. Patient with kidney problems.