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the Effect of Different Modialites of Varicocelectomy on Semen Parameters in Patient With Normal Semen Analysis

A

Assiut University

Status

Unknown

Conditions

Varicocele

Treatments

Procedure: Subinguinal varicocelectomy
Procedure: High inguinal Varicocelectomy

Study type

Observational

Funder types

Other

Identifiers

NCT03281915
varicocelectomy

Details and patient eligibility

About

to evalute the effect inguinal and subinguinal approach of varicoceclectomy on semen parameter for patients complaining of varicocele with normal semen parameter (pain is the main complaint)

Full description

the varicocele is defined as dilated and incompetent veins within the pampiniform plexus of spermatic cord. varicocele has been described as the most common surgically correctable cause of male subinfertility.this is a disease that devolops during puberty when both endocrine and exocrine function of the testicle dramatically increases, along with testicular blood flow. varicocele only rarely detected in boys less than 10 years. left sided varicocle found in 15% of healthy young men.incontrast, the incidence in sub fertile men approaches 40% bilateral varicocele is uncommon in healthy men (less than 10%) but palpated in 20% in sub fertile men. in-general varicocele don't spontaneously regress. an accurate physical examination remain the corner stone of varicocele diagnosis.

several anatomic features contribute to the predominance of left sided varicocele is the left intrnal spermatic vein longer than the right and it typically joins the left renal vein at a right angle.as result of this character higher venous pressures fair transmited to the left spermatic vein and result in reterograde reflux of blood.

varicocle are associated with testicular atrophhy and varicocle correction can reverse atrophy in adolececnt. there is strong evidence affect semen quality it can cause abnormalties in concentration, motility and morphology.main defect is the motility.

indication of varicocelectomy:

  1. Large varicoceles in adolescents
  2. Childhood varicocele with testicular atrophy
  3. Varicoceles with elevated FSH values, or low testosterone levels
  4. Varicoceles with scrotal pain
  5. Cosmetic indication
  6. Male infertility with pathological semen analysis and varicocele

Enrollment

32 estimated patients

Sex

Male

Ages

19 to 45 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • age more than 19 years old
  • primary varicocele

Exclusion criteria

  • secondary varicocele recurrent varicocele age less than 19 years

Trial design

32 participants in 2 patient groups

high inguinal approch
Description:
Patients undergoing high inguinal varicocelectomy with normal pre operative semen parameters, post operative semen analysis parameters will be recorded
Treatment:
Procedure: High inguinal Varicocelectomy
subinguinal approch
Description:
Patients undergoing subinguinal varicocelectomy with normal pre operative semen parameters, post operative semen analysis parameters will be recorded
Treatment:
Procedure: Subinguinal varicocelectomy

Trial contacts and locations

1

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Central trial contact

Abdelrahman M Abdelkader; Mohamed A Osman, professor

Data sourced from clinicaltrials.gov

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