The Effect of Different Treatment Modalities of Tubal Ectopic Pregnancy on Ovarian Reserve: a Prospective Cohort Study

Assiut University

Status: Enrolling

Conditions: Ectopic Pregnancy

Treatments: Diagnostic Test: Amh hormone

Study type: Observational

Funder types: Other

Identifiers

NCT06471166

Ectopic pregnancy

Details and patient eligibility

About

Detect the effect of different treatment modalities of tubal ectopic pregnancy on ovarian reserve

Enrollment: 90 estimated patients

Sex: Female

Ages: 18 to 44 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• The study will include patients aged 18-44 years with known diagnosis or suspicion of diagnosis of tubal ectopic pregnancy (abnormal doubling rates of their b-HCG levels as well as ultrasonographically identified or unidentified gestational sacs outside the uterus)
• Included patients must have capacity to provide informed consent. Given the potential emergent nature of presentation, women will not be recruited if fully informed consent could be compromised due to a highly distressed emotional state or significant hemorrhage necessitating the need for urgent surgery

Exclusion criteria

1. The use of hormonal contraceptives within two months of enrolment
2. If other surgery was conducted at the time of salpingectomy.
3. If a woman was pregnant at follow up visit for AMH measurement
4. History of previous surgeries of fallopian tubes and/or ovaries

Trial design

90 participants in 6 patient groups

Conservative management

Treatment:

Diagnostic Test: Amh hormone

Medical treatment

Treatment:

Diagnostic Test: Amh hormone

Surgical treatment (Open or laparoscopic salpingectomy)

Treatment:

Diagnostic Test: Amh hormone

Surgical treatment after failed medical treatment (Open or laparoscopic salpingectomy)

Treatment:

Diagnostic Test: Amh hormone

Conservative surgical treatment (salpingotomy, salpingostomy, tubal milking)

Treatment:

Diagnostic Test: Amh hormone

Conservative surgical treatment after failed medical treatment

Treatment:

Diagnostic Test: Amh hormone