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The Effect of Eating Frequency on Blood Pressure

Imperial College London logo

Imperial College London

Status

Withdrawn

Conditions

Blood Pressure

Treatments

Other: dietary intervention

Study type

Interventional

Funder types

Other

Identifiers

Details and patient eligibility

About

The primary purpose of this study is to identify the effect of meal frequency on blood pressure (BP) levels of individuals.

Full description

Migration studies, observational epidemiology and clinical trial data indicate that causes of adverse BP levels are mainly environmental , including lifestyle under which dietary factors play a role. Therefore, lifestyle modification is part of the current American Heart Association recommendations for prevention and control of adverse BP levels.

Although the effects of nutrients and foods on BP have been studied extensively, other dietetic factors such as eating frequency and number of meals in a day have been less thoroughly investigated and warrant further research to explore their possible positive effect on BP.

Sex

All

Ages

35 to 70 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Healthy individuals aged 35-70 years with prehypertension (systolic/diastolic BP 120-139/80-89 mm Hg) BMI 20-30 kg/m2 non-smoking non alcoholic drinkers

Exclusion criteria

  • Weight change of ≥ 3kg in the preceding 2 months
  • Current smokers
  • Substance abuse
  • Alcohol intake
  • Pregnancy
  • Diabetes
  • Cardiovascular disease
  • Cancer
  • Gastrointestinal disease e.g. inflammatory bowel disease or irritable bowel syndrome
  • Kidney disease
  • Liver disease
  • Pancreatitis
  • Use of medications including: anti inflammatory drugs or steroids, antihypertensive drugs, cholesterol lowering medication, androgens, phenytoin, erythromycin or thyroid hormones.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

None (Open label)

0 participants in 2 patient groups

low frequency diet
Experimental group
Description:
Participants will be assigned to a low frequency diet (fixed energy intake)
Treatment:
Other: dietary intervention
High frequency diet
Experimental group
Treatment:
Other: dietary intervention

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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