The Effect of Environmental Factors on Colorectal Cancer Based on Macrogenomes

Dong Peng

Status: Active, not recruiting

Conditions: Colon Cancer; Rectal Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT06852495

2024-443-01

Details and patient eligibility

About

The aim of this study is to investigate the effects of environmental factors, such as air pollution, on the occurrence, development and prognosis of colorectal cancer; to identify metabolic markers specific to colorectal cancer patients, which will provide a basis for early diagnosis, early intervention and individualized treatment; and to comprehensively understand the mechanism of the occurrence and development of colorectal cancer by integrating the data of environmental factors and the macro-genome, and to develop new predictive and therapeutic strategies.

Enrollment: 200 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age ≥18 years old;
• Patients diagnosed with colorectal cancer by pathologic biopsy before surgery;
• Patients did not undergo chemotherapy, radiotherapy, targeted and immunotherapy, etc. before enrollment;
• Willing to participate in the study and sign an informed consent form. Complete clinical data.

Exclusion criteria

• Concurrent primary malignant tumor other than colorectal cancer;
• Patients with severe cardiopulmonary insufficiency or other systemic diseases that affect the choice of treatment plan;
• Inappropriate for enrollment as assessed by the investigator;
• Incomplete clinical data.

Trial design

200 participants in 2 patient groups

the colorectal cancer group

Description:

patients diagnosed with colorectal cancer

the control group

Description:

Healthy individuals with no history of malignant tumor