The Effect of Environmental Factors on Gastric Cancer Based on Macrogenome

Dong Peng

Status: Active, not recruiting

Conditions: Air Pollution; Gastric Cancers

Treatments: Diagnostic Test: gastric cancer; Diagnostic Test: healthy

Study type: Observational

Funder types: Other

Identifiers

NCT06854146

2024-444-01

Details and patient eligibility

About

The objectives of this study were to clarify how environmental factors such as air pollution affect the occurrence and development of gastric cancer; to identify patient-specific macrogenomic markers of gastric cancer; and to investigate the mechanism of gastric cancer development based on environmental factors and macrogenomic data.

Enrollment: 200 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• age ≥ 18 years;
• patients with preoperative diagnosis of gastric cancer confirmed by pathologic biopsy;
• no chemotherapy, radiotherapy, targeted and immunotherapy, etc. before enrollment;
• willing to participate in the study and sign the informed consent form;
• complete clinical data.

Exclusion criteria

• concurrent primary malignant tumor other than gastric cancer;
• patients with systemic diseases, such as severe cardiopulmonary;
• insufficiency, that affect the choice of treatment plan;
• not suitable for enrollment as assessed by the investigator;
• incomplete clinical data.

Trial design

200 participants in 2 patient groups

gastric cancer group

Description:

patients diagnosed with gastric cancer

Treatment:

Diagnostic Test: gastric cancer

control group

Description:

healthy participants

Treatment:

Diagnostic Test: healthy