The Effect of Epidural Steroid Use in Patients With Continous Epidural Block in PHN Patients.

Korea University

Status and phase: Unknown; Phase 4

Conditions: Neuralgia,Postherpetic

Treatments: Drug: Dexamethasone; Drug: Ropivacaine

Study type: Interventional

Funder types: Other

Identifiers

NCT03995563

2019-04-011

Details and patient eligibility

About

The efficiency of epidural steroid injection in patients who has postherpetic neuralgia is well known. In this study, the purpose is whether the continous epidural steroid injection is effective or not.

Full description

Continous epidural injection will be done during 10 days. D group will be injected a 0.19% ropivacaine 8mL and dexametasone 1mg every other day during 10 days.

Continous epidural injection will be done during 10 days N group will be injected a 0.19% ropivacaine 8mL only every other day during 10 days

Enrollment: 40 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who has herpes zoster
• Patients has a period (at least 1month) after onset of herpes zoster
• Patients has a definite symptom along dermatome
• ASA class I - II
• Age : 18 - 80 years

Exclusion criteria

• Patients who has a cancer
• Patients who has a neurologic, psychologic, renal, hepatic and hematologic disease
• Patients who has a other dermatologic disease
• Patients who has major operation & procedure history
• Patients who has a other pain origin
• Patients who can not be inserted epidural catheter

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 2 patient groups, including a placebo group

D group

Active Comparator group

Description:

0.19% Ropivacaine 8mL + Dexametasone 1mg every other day injection during 10 days

Treatment:

Drug: Ropivacaine

Drug: Dexamethasone

N group

Placebo Comparator group

Description:

0.19% Ropivacaine 8mL only every other day injection during 10 days

Treatment:

Drug: Ropivacaine