The Effect of Esophageal Doppler Guided Goal-directed Hemodynamic Therapy in Severe Trauma Patients (GDT)

Ajou University School of Medicine

Status: Completed

Conditions: Trauma

Treatments: Device: esophageal Doppler

Study type: Observational

Funder types: Other

Identifiers

NCT03339375

MED-OBS-17-314

Details and patient eligibility

About

Prospective randomized clinical trial Compare the goal-directed fluid therapy using esophageal Doppler and classic fluid therapy

Full description

Goal directed fluid therapy becomes issue for enhanced recovery after surgery. In goal directed therapy, dynamic parameters, like stroke volume and cardiac output, is important. Esophageal Doppler is one of device which provides dymanic parameters.

In severe trauma cases, the effect of goal directed therapy is not known yet. So the aim of this study is comparing the results of goal directed therapy using esophageal Doppler and conventional fluid therapy.

Enrollment: 46 patients

Sex: All

Ages: 20 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Severe trauma patients who undergo general anesthesia
• Initial serum lactate level > 2mmol/L

Exclusion criteria

• Severe traumatic brain injury
• THoracic surgery
• Age < 19 years old
• Impending arrest or post CPR state
• Severe facial trauma

Trial design

46 participants in 2 patient groups

control

Description:

Monitoring arterial pressure, central venous pressure and pulse pressure variation

esophagela Doppler

Description:

Monitoring arterial pressure, central venous pressure Insertion of esophageal Doppler probe to patient Monitoring stroke volume, cardiac output, corrected flow time from esophageal Doppler Use stroke volume optimization goal directed therapy protocol

Treatment:

Device: esophageal Doppler