The Effect of Exercises of Different Intensity Applied After Total Knee Arthroplasty on Exercise-Induced Hypoalgesia

Hacettepe University

Status: Completed

Conditions: Pain, Acute; Knee Osteoarthritis

Treatments: Behavioral: High Intensity Exercises Program; Behavioral: Low Intensity Exercises Program

Study type: Interventional

Funder types: Other

Identifiers

NCT05781230

126

Details and patient eligibility

About

The aim of this study was to investigate whether exercise-induced hypoalgesia (EIH) is present following exercise in patient after total knee arthroplasty (TKA) and if so, if it changes with exercise intensity. A repeated measures and single-blinded randomized study were done. Thirty-eight patients 24 hours after TKA were randomly assigned to either low intensity exercises (LIE) group or high intensity exercises (HIE) group. An exercise programs lasted for five days during the hospitalization period. Pain severity was assessed by Visual Analog Scale (VAS) (0-10 mm). Pressure pain thresholds (PPTs) were measured over quadriceps and biceps brachii and muscles immediately before and after exercise.

Full description

Background: The aim of this study was to investigate whether exercise-induced hypoalgesia (EIH) is present following exercise in patient after total knee arthroplasty (TKA) and if so, if it changes with exercise intensity.

Methods : A repeated measures and single-blinded randomized study were done. Thirty-eight patients 24 hours after TKA were randomly assigned to either low intensity exercises (LIE) group or high intensity exercises (HIE) group. An exercise programs lasted for five days during the hospitalization period. Pain severity was assessed by Visual Analog Scale (VAS) (0-10 mm). Pressure pain thresholds (PPTs) were measured over quadriceps and biceps brachii and muscles immediately before and after exercise.

Enrollment: 38 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients had undergone primary unilateral total knee replacement surgery
• Patients hospitalized for at least seven days were enrolled in this study.

Exclusion criteria

• Medically stable patients who used glucocorticoids or strong analgesic drugs
• Patients had post-traumatic OA, rheumatoid arthritis (RA), psoriatic arthritis, cognitive, hearing and visual problems Patients were diagnosed chronic pain condition were excluded from the study.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

38 participants in 2 patient groups

HIE program

Experimental group

Description:

HIE program ; High Intensity Exercises Program. 3 sets of 15 repetition

Treatment:

Behavioral: High Intensity Exercises Program

Behavioral: Low Intensity Exercises Program

LIE Program

Experimental group

Description:

Low Intensity Exercises program 2 sets of 8 repetition

Treatment:

Behavioral: High Intensity Exercises Program

Behavioral: Low Intensity Exercises Program