The Effect of Exercises on Physiological Changes and Clinical Symptoms in Allergic Rhinitis Patients

Chulalongkorn University

Status: Completed

Conditions: Allergic Rhinitis

Treatments: Other: Aerobic exercise with Vit. C; Other: Aerobic exercise; Other: No exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT02123914

SPSC-2

Details and patient eligibility

About

1. Moderate exercise training decrease cytokine response and rhinitis symptoms in patients with allergic rhinitis
2. Moderate exercise training combined with vitamin C supplementation decrease cytokine response and rhinitis symptoms in patients with allergic rhinitis
3. Moderate exercise training combined with vitamin C supplementation has more beneficial effects than moderate exercise training alone for decreasing cytokine response and rhinitis symptoms in patients with allergic rhinitis

Enrollment: 27 patients

Sex: All

Ages: 18 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

The inclusion criteria included patients with allergic rhinitis who had a clinical history of persistent rhinitis, and had positive skin prick test (wheal diameter ≥ 3 mm) to house dust mite (D. pteronyssinus).

Exclusion criteria

Subjects with known asthma, chronic rhinosinusitis, hypertension or cardiovascular diseases were excluded.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: Single Blind

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27 participants in 2 patient groups

Aerobic exercise with Vit. C & Aerobic exercise

Experimental group

Treatment:

Other: Aerobic exercise

Other: Aerobic exercise with Vit. C

exercise without vit. c supplement & no exercise

Active Comparator group

Treatment:

Other: Aerobic exercise with Vit. C

Other: No exercise