The Effect of Fat on Vitamin D Absorption (VITD_100484)

Federal University of Rio Grande do Sul

Status: Completed

Conditions: Vitamin D Deficiency

Treatments: Dietary Supplement: Vitamin D3; Dietary Supplement: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT01519986

VITD_100484

Details and patient eligibility

About

The purpose of this study is to evaluate the absorption of dietary supplement of vitamin D3 (cholecalciferol), through the variation of 25 (OH) D levels, as the fat content of the meal associated with the administration of the supplement.

Enrollment: 64 patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Residents of the hospital clinics of Porto Alegre

Exclusion criteria

• Don't drink milk
• Obesity
• Malnutrition
• Liver disease
• Kidney disease or diabetes
• Use of dietary supplements containing calcium and vitamin D
• Medications
• Anticonvulsants
• Barbiturates, or steroids.
• Having performed a journey the last four months to locations near the Earth's equatorial plane, due to sun exposure that may have occurred during this period, or vacations planned during the study period.

Trial design

64 participants in 3 patient groups

Low fat Meal

Experimental group

Description:

50,000 UI vitamin D3 with low fat meal

Treatment:

Dietary Supplement: Vitamin D3

Dietary Supplement: Placebo

Medium fat meal

Experimental group

Description:

50,000 UI vitamin D3 with medium fat meal

Treatment:

Dietary Supplement: Vitamin D3

Dietary Supplement: Placebo

High fat meal

Experimental group

Description:

50,000 UI vitamin D3 with high fat meal

Treatment:

Dietary Supplement: Vitamin D3

Dietary Supplement: Placebo